FACTOR PROMOTING WOUND HEALING: RADICAL SCAVENGING AND ANTI-INFLAMMATORY ACTIVITY AND GROWTH FACTOR PROMOTION OF HELIOTROPIUM INDICUM
نویسندگان
چکیده
منابع مشابه
Studies on Wound Healing Activity of Heliotropium indicum Linn. Leaves on Rats
The petroleum ether, chloroform, methanol, and aqueous extracts of Heliotropium indicum Linn. (Family: Boraginaceae) were separately evaluated for their wound healing activity in rats using excision (normal and infected), incision, and dead space wound models. The effects of test samples on the rate of wound healing were assessed by the rate of wound closure, period of epithelialisation, wound ...
متن کاملTransforming Growth Factor-β and Endoglin Signaling Orchestrate Wound Healing
Physiological wound healing is a complex process requiring the temporal and spatial co-ordination of various signaling networks, biomechanical forces, and biochemical signaling pathways in both hypoxic and non-hypoxic conditions. Although a plethora of factors are required for successful physiological tissue repair, transforming growth factor beta (TGF-β) expression has been demonstrated throug...
متن کاملCopper-induced vascular endothelial growth factor expression and wound healing.
Angiogenesis plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear...
متن کاملFOXN1 Transcription Factor in Epithelial Growth and Wound Healing.
FOXN1 is a prodifferentiation transcription factor in the skin epithelium. Recently, it has also emerged as an important player in controlling the skin wound healing process, as it actively participates in reepithelialization and is thought to be responsible for scar formation. FOXN1 positivity is also a feature of pigmented keratinocytes, including nevi, and FOXN1 is an attribute of benign epi...
متن کاملLysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor.
PURPOSE To identify the underlying mechanisms by which lipid mediator lysophosphatidic acid (LPA) acts as a growth factor in stimulating extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3'-kinase (PI3K) during corneal epithelial wound healing. METHODS Epithelial debridement wounds in cultured porcine corneas and scratch wounds in an epithelial monolayer of SV40-immortalize...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2019
ISSN: 0975-7058
DOI: 10.22159/ijap.2019.v11s5.t0044